Bisphosphonates adverse event rate differences

2018-11-23

Rate in treatment arm minus rate in control arm.

Including only studies with a placebo or other non-biphosphonate control.

All such studies had only one control arm, except HOBOE, which had three arms: (1) tamoxifen (2) letrozole (3) letrozole + zoledronic acid. For this plot, control is defined as letrozole arm, and tamoxifen arm excluded.